If you could only have one last chance to share your knowledge with the world, what would you say and want your legacy to be? This is the basic idea behind the generic "Last Lecture" given by some renowned professors.
Randy Pausch was a Professor for Computer Science and Human-Computer Interaction at Carnegie Mellon University. Unfortunately, for Prof. Pausch it became a reality. He was diagnosed with pancreatic cancer and soon it turned terminal. He accepted to give the lecture before he knew that his cancer will prove fatal. Indeed, it really was a Last Lecture.
He gave a talk about "Achieving Your Childhood Dreams" on September 18th, 2007. The lecture is given below: